In 2008, Northeastern's School of Technological Entrepreneurship received a grant to design and develop a multidisciplinary new product development course for technology entrepreneurship. In this session, we will review how the class was created, implemented, and received by students, faculty, administration, and industry. The transformational class expanded on traditional content by 1) developing baseline content of general product development practices that are common to all development projects, 2) developing tailored course content for specific technologies (such as biotechnology and software), and 3) initiating a funded multidisciplinary experiential project during the course, resulting in industry-quality prototypes.The course was developed and run in conjunction with the Massachusetts College of Art and Design. The combination of engineering, industrial design, and entrepreneurship has been extremely successful from a pedagogical and student project perspective. From our session, it our hope that this model can be recreated nationwide.